State Goal Content
Reasons for establishing the human genome project, Recognition that the project is useful in determining whether individuals may carry genes for genetic conditions and in developing gene therapy. Applications of Biotechnology: Gel electrophoresis as a technique to separate molecules based on size (students are not expected to know the steps of gel electrophoresis in order or great detail, Uses of DNA Fingerprinting, Applications of transgenic organisms (plants animals and bacteria) in agriculture and industry including pharmaceutical applications such as the production of human insulin, Ethical issues and implications of genomics and biotechnology, (stem cell research and genetically modified organisms)
Written Explanation
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Lessons and Lesson Plans
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Activities
Stem Cell Therapies Today - Online Activity
Visualizing Gene Expression - Online Activity
Transgenic Fly Virtual Lab
1. Anticipatory Set: Video clip segment “Stepford Wives”
Students will create a (class / team product): Research and share ethical issues in science such as cloning, eugenics, genetic engineering, genetic testing, etc.
Multicultural and/or ESL and/or Bilingual Link: Design punnett squares showing possibility of culturally linked or sexually genetic disorders such as hemophilia, color blindness, etc.
Mathematics/Science Link and/or Humanities Link:
School-to-Career/Tech Prep Link: Invite geneticist to speak to classes
2. Anticipatory set: Video clip Gatica (genetically engineered world) and discuss overall view of genetic engineering.
Students will: Debate pros and cons of mandatory genetic testing of convicted felons
Class/team/individual product: Take a view opposite of their own and convince others of this view (related to eugenics)
INDIVIDUAL JOURNAL ASSIGNMENT: Write a letter to a pregnant mother encouraging her to have an amniocentesis (prenatal genetic test)
HOMELINK: Students will create a pedigree (note any prevalent disorders).
Pictures & Graphics
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Animations, Movie Clips & Sounds
Selective Breeding - Corn
Selective Breeding - Dogs
Planarian Regenerationi Stem Cells
Cultured Human Stem Cells
Somatic Cell Nuclear Transfer
Gene Chip Explanation
Antlers and Mammalilan Regeneration
Transgenic Mice
Gene Chip Manufacturing
Clonal vs Sexual Reproduction
Intracytoplasmic Sperm Injections
Sperm Motility
Creating Embryonic Stem Cell Lines
Somatic Cell Nuclear Transfer Animation
Essential Questions
1. A major university in unconcerned about the public perception of its course offering. The university depends on community financial support. Should courses such as Cloning 101, Eugenics 159, and selective genetics be dropped from the course offerings to appease community leaders? What would you do?
2. A prenatal test exists to detect a rare genetic disease that causes deformation of limbs, major heart defects, and undevelopment of the lungs in the infant. Doctor’s believe an unborn infant has the disorder. The mother refuses to take the prenatal test. Should she be forced to take the test?
3. You receive a communication about someone you know via e-mail which contains information of an embarrassing nature, which might be true or not. What will you do about with the e-mail?
Test Items
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Formative Assessments
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Other Resources
Gene Therapy - Wikipedia
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